Know what's inside.
CD-Leiste

Preclinical Services

Since nearly 20 years the GBA Pharma site in Saarbrücken has been your reliable partner for your non-clinical drug development projects. We offer high quality off-the-shelf assays as well as customized R&D services. Our assays support exploratory research and meet regulatory demands. We provide GxP and non-GxP bio­analytical services.

At GBA Pharma we go the extra mile to deliver solutions to our clients. We make your goals our goals and become a part of your team. Our staff has a long track record in drug discovery and development. We innovatively combine and tailor assays to address your project-specific demands.

A long standing experience with small molecules, biologicals e.g. proteins and peptides combined with leading edge technology allows us to deliver high quality data. Our flexible and highly-skilled team is looking forward to support your discovery and preclinical projects.

The service portfolio covers the complete drug discovery and development testing program, in vitro, in vivo, ex vivo and bioanalysis:

In vitro studies for the evaluation of potency and safety of potential new drugs
  • In vitro ADMET (absorption, distribution, metabolism, elimination & toxicology)
  • In vitro potency studies
In vivo drug metabolism and pharmacokinetics (DMPK)
  • State-of-the-art in vivo PK studies with rodents and further clinically relevant species*
  • Customized in vivo pharmacodynamic solutions
  • In vivo toxicology studies (GLP & non-GLP*)
  • In house quantification of parent compound, metabolites & biomarkers
  • PK parameter calculation (Kinetica, WiNonLin)
Bioanalytical services for internal and external samples including clinical samples
  • Small molecules: HPLC-MS/MS, UHPLC-MS/HRMS (Triple Quadrupole & Orbitrap Q-Executive instruments)
  • Biologicals: Immuno-based technologies (ELISA, Luminex), Q-Executive Plus for quantification of molecules up to 60 kDa without prior digestion

*conducted in cooperation with a German partner laboratory

Brands of the
GBA PHARMA Division